openpharma/crmPack

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Object-Oriented Implementation of CRM Designs

Stars: 22
Forks: 14
Open beginner issues: 0
Indexed issues: 80
Avg merge: 1d 23h
Merged PRs (30d): 5

Dominant language: HTML
License: No license data
Last GitHub push: Sep 18, 2026
Latest indexed: Sep 19, 2026
Contributing guide: No contributing guide
Code of conduct: No code of conduct
Beginner labels: good first issue help wanted

Beginner friendly Everything

Open All

80 open issues indexed

Restructure plots for NextBest classes Open

enhancement high priority

Difficulty 5/5 Over a week Newbie friendliness 35/100

openpharma/crmPack#967 · Opened Sep 9, 2026
Add multiple chains option Open

enhancement high priority

Difficulty 5/5 Over a week Newbie friendliness 30/100

openpharma/crmPack#963 · Opened Jul 30, 2026
Dose combination: consider saturated model Open

enhancement

Difficulty 5/5 Over a week Newbie friendliness 25/100

openpharma/crmPack#955 · Opened Jul 11, 2026
Improve JAGS code readability by adding section comments Open

documentation

Difficulty 3/5 1-2 days Newbie friendliness 35/100

openpharma/crmPack#954 · Opened Jul 9, 2026
TiteCRM vignette minor improvement Open

Difficulty 1/5 Under an hour Newbie friendliness 78/100

openpharma/crmPack#941 · Opened Apr 9, 2026
Implement `knit_print` for subclasses of `Simulations` (including tests) Open

openpharma/crmPack#930 · 1 assignee · Opened Jan 26, 2026
Mocking PRNGs in unit tests Open

discussion

Difficulty 4/5 3-5 days Newbie friendliness 35/100

openpharma/crmPack#918 · 3 comments · Opened Dec 5, 2025
enable snapshot comparisons in tests run on GHA Open

cleanup

Difficulty 3/5 1-2 days Newbie friendliness 38/100

openpharma/crmPack#914 · Opened Nov 30, 2025
`simulate` method for `DesignOrdinal` Open

enhancement

Difficulty 3/5 1-2 days Newbie friendliness 35/100

openpharma/crmPack#890 · 3 comments · Opened Nov 13, 2025
Prototype code that could go into simulations table generation Open

enhancement

Difficulty 5/5 Over a week Newbie friendliness 20/100

openpharma/crmPack#878 · 1 comment · Opened Sep 23, 2025
Proposal to support BOIN methodology Open

design enhancement high priority

openpharma/crmPack#872 · 1 comment · 1 reaction · 2 assignees · Opened Mar 13, 2025
Add `max.len`, `min.len` and `length` arguments to `check_probabilties()` et al Open

enhancement good first issue low priority

Difficulty 4/5 3-5 days Newbie friendliness 35/100

openpharma/crmPack#862 · Opened Sep 24, 2024
Refactor `DesignOrdinal` Open

enhancement

Difficulty 4/5 3-5 days Newbie friendliness 35/100

openpharma/crmPack#856 · Opened Sep 11, 2024
Add support for "smallest/largest next best" dose Open

enhancement

openpharma/crmPack#855 · 8 comments · 1 assignee · Opened Sep 11, 2024
Output from `tidy-IncrementsRelativeParts` is sub-optimal Open

enhancement good first issue low priority

Difficulty 3/5 1-2 days Newbie friendliness 35/100

openpharma/crmPack#788 · 1 comment · Opened Feb 6, 2024
Suggestion: DLT profile plot and Prob(DLT) plot with shaded loss areas Open

enhancement parked

openpharma/crmPack#783 · 2 comments · 1 assignee · Opened Jan 25, 2024
Implement `knit_print` and `render` methods for reporting Open

enhancement good first issue help wanted high priority

openpharma/crmPack#774 · 1 comment · 1 assignee · Opened Jan 16, 2024
Create `simulate` method for ordinal CRM models Open

blocked enhancement

Difficulty 5/5 Over a week Newbie friendliness 25/100

openpharma/crmPack#764 · Opened Dec 4, 2023
Create `examine` method for ordinal CRM models Open

enhancement

Difficulty 5/5 Over a week Newbie friendliness 25/100

openpharma/crmPack#763 · 1 comment · Opened Dec 4, 2023
Add methods to report posterior mean and covariance of model parameters Open

enhancement good first issue low priority

Difficulty 3/5 1-2 days Newbie friendliness 42/100

openpharma/crmPack#757 · Opened Nov 29, 2023
Explore options for supporting non-diagonal covariance matrices for ordinal models Open

discussion enhancement help wanted low priority

Difficulty 5/5 Over a week Newbie friendliness 25/100

openpharma/crmPack#755 · Opened Nov 29, 2023
Allow `tidy-Samples` to return fitted probabilities of toxicity Open

enhancement low priority

Difficulty 5/5 Over a week Newbie friendliness 35/100

openpharma/crmPack#749 · Opened Nov 24, 2023
Testing for method existence Open

enhancement

Difficulty 4/5 3-5 days Newbie friendliness 35/100

openpharma/crmPack#734 · Opened Nov 9, 2023
Improve examples that use a rigid design Open

documentation high priority

openpharma/crmPack#679 · 1 comment · 1 reaction · 1 assignee · Opened Sep 21, 2023
Design for reporting designs and results according to CONSORT-DEFINE and SPIRIT-DEFINE standards Open

design enhancement SP8

Difficulty 5/5 Over a week Newbie friendliness 25/100

openpharma/crmPack#670 · 1 comment · Opened Sep 11, 2023
Include remark about informative Gamma prior for lambda in rolling CRM vignette Open

documentation ROLLING CRM

Difficulty 2/5 1-3 hours Newbie friendliness 35/100

openpharma/crmPack#636 · Opened Jun 24, 2023
`DALogisticLogNormal` improve features: interval probability calculation, parameter `l` Open

enhancement ROLLING CRM

Difficulty 4/5 3-5 days Newbie friendliness 35/100

openpharma/crmPack#634 · Opened Jun 24, 2023
Add better documentation / explanation for `c_par` in `DALogisticLogNormal` Open

documentation enhancement ROLLING CRM SP2

Difficulty 2/5 1-3 hours Newbie friendliness 65/100

openpharma/crmPack#629 · Opened Jun 24, 2023
Add `points` argument to `simulate` methods Open

enhancement IMPROVEMENTS

Difficulty 4/5 3-5 days Newbie friendliness 38/100

openpharma/crmPack#618 · Opened Jun 23, 2023
Add in the O.C. report number of times the model is overruled Open

enhancement IMPROVEMENTS

Difficulty 4/5 3-5 days Newbie friendliness 30/100

openpharma/crmPack#617 · 2 comments · Opened Jun 23, 2023
Add warning if the MinimalInformative returns a strong prior Open

enhancement IMPROVEMENTS

Difficulty 4/5 3-5 days Newbie friendliness 35/100

openpharma/crmPack#616 · Opened Jun 23, 2023
Add in O.C. report the frequency of simulated trials selecting the correct OBD or the dual endpoint models Open

enhancement IMPROVEMENTS

Difficulty 4/5 3-5 days Newbie friendliness 35/100

openpharma/crmPack#615 · Opened Jun 23, 2023
Produce by default a comparison graph for minimalInformative function Open

enhancement IMPROVEMENTS

Difficulty 3/5 1-2 days Newbie friendliness 35/100

openpharma/crmPack#614 · 1 comment · 1 reaction · Opened Jun 23, 2023
Improve documentation of the log transformation for `LogisticLogNormal` etc. Open

documentation IMPROVEMENTS SP1

Difficulty 1/5 Under an hour Newbie friendliness 45/100

openpharma/crmPack#613 · Opened Jun 23, 2023
Optimize refDose for quantile->logistic functions Open

enhancement IMPROVEMENTS

Difficulty 4/5 3-5 days Newbie friendliness 25/100

openpharma/crmPack#612 · Opened Jun 22, 2023
Allow simple construction of a prior based on historical data Open

design enhancement NEW FEATURES

Difficulty 5/5 Over a week Newbie friendliness 25/100

openpharma/crmPack#610 · 1 comment · Opened Jun 22, 2023
Design for simplified running of simulations on a cluster Open

design NEW FEATURES

Difficulty 5/5 Over a week Newbie friendliness 35/100

openpharma/crmPack#609 · Opened Jun 22, 2023
Production of Word output tables from simulation summaries Open

design enhancement NEW FEATURES

openpharma/crmPack#608 · 2 comments · 1 assignee · Opened Jun 22, 2023
Add slide production with ReporteRs package examples Open

design enhancement NEW FEATURES

Difficulty 3/5 1-2 days Newbie friendliness 30/100

openpharma/crmPack#605 · 2 comments · Opened Jun 22, 2023
Add additional unit tests for some stopping rules Open

Difficulty 4/5 3-5 days Newbie friendliness 30/100

openpharma/crmPack#600 · Opened Jun 16, 2023
Possibly suboptimal definitions in `setGeneric` Open

Difficulty 4/5 3-5 days Newbie friendliness 45/100

openpharma/crmPack#599 · Opened Jun 16, 2023
Provide functions to determine if a proposed design is rigid or incoherent Open

enhancement

Difficulty 3/5 1-2 days Newbie friendliness 48/100

openpharma/crmPack#569 · Opened May 15, 2023
Messages provided by `stopTrial` for `StoppingMaxGainCIRatio` are badly formatted Open

Difficulty 2/5 1-3 hours Newbie friendliness 45/100

openpharma/crmPack#566 · Opened May 12, 2023
Moving to `roxytypes`, `roxylint` Open

documentation

Difficulty 4/5 3-5 days Newbie friendliness 25/100

openpharma/crmPack#551 · Opened Apr 28, 2023
Proposal: Reworking interface for providing JAGS code Open

enhancement

Difficulty 5/5 Over a week Newbie friendliness 25/100

openpharma/crmPack#550 · 2 comments · Opened Apr 28, 2023
New validation check for some of the `RuleDesign` sub-classes. Open

enhancement

Difficulty 3/5 1-2 days Newbie friendliness 35/100

openpharma/crmPack#541 · Opened Apr 18, 2023
Consistent handling of method's input that is not a regular one, i.e. `NA`, `NULL`, `empty`. Open

cleanup discussion

Difficulty 5/5 Over a week Newbie friendliness 20/100

openpharma/crmPack#523 · Opened Apr 3, 2023
Seed for simulations utilizing parallel computing and `McmcOptions` Open

enhancement

Difficulty 1/5 1-3 hours Newbie friendliness 38/100

openpharma/crmPack#513 · Opened Mar 27, 2023
Write a test case for user written code that is used with parallel computing Open

enhancement

openpharma/crmPack#512 · 1 assignee · Opened Mar 27, 2023
Refactor four `Increments` subclasses Open

cleanup discussion low priority

Difficulty 5/5 Over a week Newbie friendliness 25/100

openpharma/crmPack#509 · 2 comments · Opened Mar 27, 2023

openpharma/crmPack

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