RosettaCommons/rosetta

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The Rosetta Bio-macromolecule modeling package. Available through license with the University of Washington.

Stars: 470
Forks: 169
Open beginner issues: 0
Indexed issues: 25
Avg merge: 16d 23h
Merged PRs (30d): 2

Dominant language: C++
License: No license data
Last GitHub push: Sep 16, 2026
Latest indexed: Sep 20, 2026
Contributing guide: Contributing guide
Code of conduct: Code of conduct
Beginner labels: No beginner labels indexed

Beginner friendly Everything

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25 open issues indexed

Repeated RosettaDock crashes Open

Difficulty 4/5 3-5 days Newbie friendliness 35/100

RosettaCommons/rosetta#739 · 1 comment · Opened Jul 16, 2026
FastRelax on RoseTTaFold3 protein-ligand complexes Open

RosettaCommons/rosetta#721 · 2 comments · 1 assignee · Opened Jun 24, 2026
Update `aarch64` conda package Open

RosettaCommons/rosetta#584 · 1 comment · 1 reaction · 1 assignee · Opened Dec 16, 2025
using identify_cdr_cluster with pyigclassify2 Open

Difficulty 4/5 3-5 days Newbie friendliness 25/100

RosettaCommons/rosetta#552 · 2 comments · Opened Oct 28, 2025
GALigandDock shows poor compatibility with ref2015 Open

bug

RosettaCommons/rosetta#506 · 1 assignee · Opened Aug 20, 2025
ERROR Report: Assertion `res2.is_bonded(res1)` failed causing crash Open

Difficulty 4/5 3-5 days Newbie friendliness 20/100

RosettaCommons/rosetta#498 · 1 comment · Opened Aug 12, 2025
Peptide with a new crosslinker Open

Difficulty 5/5 Over a week Newbie friendliness 20/100

RosettaCommons/rosetta#475 · Opened Jul 22, 2025
GlycanDock parsing issue, `maintain_links true` ignored ? Open

Difficulty 4/5 3-5 days Newbie friendliness 35/100

RosettaCommons/rosetta#400 · Opened Apr 26, 2025
using antibody_graft Open

Difficulty 3/5 1-2 days Newbie friendliness 30/100

RosettaCommons/rosetta#398 · 2 comments · Opened Apr 22, 2025
Failed to add residue HME at position 209 to surface - cannot find radius for FE1 Open

Difficulty 3/5 1-2 days Newbie friendliness 48/100

RosettaCommons/rosetta#389 · 1 comment · Opened Apr 9, 2025
cartesian_ddg cannot mutate intact disulfide bonds Open

Difficulty 4/5 3-5 days Newbie friendliness 35/100

RosettaCommons/rosetta#343 · 1 comment · Opened Mar 4, 2025
UnfoldedStateEnergyCalculator.mpi.linuxgccrelease is not working in mpi compilation Open

Difficulty 4/5 3-5 days Newbie friendliness 25/100

RosettaCommons/rosetta#271 · 3 comments · Opened Dec 10, 2024
rna_cluster issue: Structures within same cluster have RMSD higher than cutoff Open

Difficulty 4/5 3-5 days Newbie friendliness 25/100

RosettaCommons/rosetta#267 · Opened Dec 9, 2024
Protein-Protein Docking with Spiking RAM Usage Open

Difficulty 5/5 Over a week Newbie friendliness 15/100

RosettaCommons/rosetta#266 · Opened Dec 9, 2024
Cannot create normalized xyzVector from vector of length() zero Open

Difficulty 4/5 3-5 days Newbie friendliness 25/100

RosettaCommons/rosetta#264 · 2 comments · Opened Dec 8, 2024
How to incorporate the information of base pairing probability into FARFAR2 Open

Difficulty 5/5 Over a week Newbie friendliness 20/100

RosettaCommons/rosetta#248 · Opened Nov 22, 2024
fatal: not a git repository (or any of the parent directories): .git Open

Difficulty 3/5 1-2 days Newbie friendliness 30/100

RosettaCommons/rosetta#247 · 3 comments · Opened Nov 22, 2024
Patch CTERM_AMIDATION has property issues Open

Difficulty 4/5 3-5 days Newbie friendliness 35/100

RosettaCommons/rosetta#207 · 1 comment · Opened Oct 15, 2024
Error when running replicadock2 Open

Difficulty 3/5 1-2 days Newbie friendliness 25/100

RosettaCommons/rosetta#203 · 2 comments · Opened Oct 12, 2024
MPLipidAccessibility fails when the entire pose is outside the membrane Open

bug

Difficulty 4/5 3-5 days Newbie friendliness 35/100

RosettaCommons/rosetta#195 · Opened Oct 8, 2024
CircularSpline constraint function described in docs but not present in FuncFactory Open

bug documentation

Difficulty 3/5 1-2 days Newbie friendliness 42/100

RosettaCommons/rosetta#184 · Opened Oct 1, 2024
-parser:info not functional with ligand docking setup tags Open

Difficulty 4/5 3-5 days Newbie friendliness 35/100

RosettaCommons/rosetta#175 · Opened Sep 25, 2024
Crash while using phenix.rosetta_refine Open

Difficulty 4/5 3-5 days Newbie friendliness 25/100

RosettaCommons/rosetta#173 · Opened Sep 25, 2024
Error during RNA-Protein Docking Open

Difficulty 5/5 Over a week Newbie friendliness 25/100

RosettaCommons/rosetta#149 · Opened Sep 5, 2024
BLAST version in fragmentation tools for ab initio Open

bug

Difficulty 4/5 3-5 days Newbie friendliness 25/100

RosettaCommons/rosetta#92 · 1 comment · Opened Jul 13, 2024

RosettaCommons/rosetta

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