RosettaCommons / RosettaCommons/rosetta

How to incorporate the information of base pairing probability into FARFAR2

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Dominant language
C++
Stars
470
Forks
169
Avg merge
16d 23h
Merged PRs (30d)
2

Description

Thank you for maintaining and continuously improving this incredible tool. I truly appreciate all the hard work that goes into making Rosetta so versatile and powerful.

I have a question regarding the use of base-pair probability matrices in the farfar2 fragment assembly protocol. I am interested in incorporating such information into the assembly process. Could you guide me on how this could be achieved, or point me to relevant resources or examples?

Thank you very much for your time and support. I look forward to any advice you can provide.

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by reviewing the FARFAR2 fragment assembly protocol and the issue's references to base-pair probability matrices. The scope is not defined: determine whether existing Rosetta functionality or documentation explains this integration, and clarify what implementation or guidance would count as done.

Written by the indexing model from the issue text.

Assessment

Tech stack
cpp
Domain
bioinformatics
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
20/100

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