delete a label from an issue

I'm looking for a code example of how to delete a specific label from an issue and at the same time, or just after to assign someone to the issue
thanks

Start by locating the JavaScript wrapper methods for removing a label from an issue and assigning an issue to a user. Add a concise code example covering both operations, and verify that the example matches the wrapper's existing API conventions.

索引モデルが issue の本文から書いたものです。