sdsc-ordes / sdsc-ordes/modos-api

[Feature request]: metabolomics integration

Open
#115 4 comments 0 reactions 2 assignees View on GitHub

@cmdoret is already working on this.

Since Dec 4, 2024.

enhancement
Dominant language
Python
Stars
2
Forks
1
PR merge metrics
No merged PRs in 30d

Description

Contact Details

No response

Description

These are the minimum features to efficiently embed mzTab (as standard format for exchange of metabolomics data) into MODOs:

  1. The metadata on samples and assays specified in the mzTab (MTD lines) should be available and queryable through the API. Having to download the full file (or files) and parse it externally to know what data is included kills any
  2. The API should include helpers to pull pandalized versions of the SML, SMF, SME, etc.
  3. There should be helpers to remove data that is associated with a specific sample_id (=set columns in SML and SMF to NaN). Think of a patient who decides to opt-out of a study,
  4. The mzTab file should definitely be stored within the object. How else can you ensure sync, slicing, etc of modo? I can't imagine there is no way of storing a text file into zarr arrays.
  5. There should be coherence in how sample metadata across different omics layers is represented. It should be user-friendly to obtain a single table with sample_id, patient_id, batch_id, all types of objects included, and their name id
Importance Level

High

Affected Components

No response

Technical Requirements

No response

Acceptance criteria

No response

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Assessment

This issue has not been assessed yet.

Get new issues in your inbox

A short digest of beginner-friendly GitHub issues.