openvax / openvax/varcode

Add variant and effect classes for gene fusions

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Dominant language
Python
Stars
87
Forks
28
Avg merge
3h 27m
Merged PRs (30d)
27

Description

Ideally this would allow for multi-gene fusions

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by reviewing varcode’s existing variant and effect class structure and how genomic fusions are currently represented. Identify the relevant tests or entry points before defining support for multi-gene fusions; done should mean variant and effect classes represent the requested fusion cases and the behavior is covered by tests.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
bioinformatics
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
25/100

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