openpharma / openpharma/rbmi

Return frequentist MMRM model object

Open
#274 9 comments 0 reactions 0 assignees View on GitHub

Nobody has claimed this yet.

enhancement priority
Dominant language
R
Stars
21
Forks
12
PR merge metrics
No merged PRs in 30d

Description

Hi @wolbersm ,

We have been asked a few times by Paul to add return the model object of the MMRM fit for the bootstrap methods for diagnostic / residual purposes.

Talking to @nociale our current proposal would be that we return the MMRM fit to the original dataset (only) for the condmean jackknife + bootstrap methods, for all other methods (bayesian, approx bayes, blmi) we would carry on returning nothing.

What do you think ?

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by locating the MMRM fit and the condmean jackknife and bootstrap methods in the rbmi package. Determine how those methods currently return results and how Bayesian, approximate Bayesian, and BLMI methods differ. Done means agreeing on the returned original-dataset MMRM object and its behavior across these methods, then covering that contract with tests.

Written by the indexing model from the issue text.

Assessment

Tech stack
r
Domain
data
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
20/100

Get new issues in your inbox

A short digest of beginner-friendly GitHub issues.