openpharma / openpharma/RobinCar2

SE for marginal mean

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Dominant language
R
Stars
14
Forks
3
Avg merge
3d 19h
Merged PRs (30d)
1

Description

SE for marginal mean should always be calculated by cvovG, because vcovHC won't work (vcovHC only works for "difference" contrast and linear model without treatment by covariate interactions). This needs to be fixed as discussed in our meeting today.

Thanks!
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First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by locating the marginal mean standard-error calculation and the uses of cvovG and vcovHC. Check how treatment-by-covariate interactions and difference contrasts are handled, then confirm that marginal means always use cvovG and verify the affected calculations with the project's existing checks.

Written by the indexing model from the issue text.

Assessment

Tech stack
r
Domain
data
Issue type
Bug
Difficulty
4/5
Estimated time
3-5 days
Activity status
Stale
Clarity
Mostly clear
Newbie friendliness
38/100

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