openpharma / openpharma/DoseFinding

Vignette + function for ERP sample size calculation

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Dominant language
R
Stars
14
Forks
0
PR merge metrics
No merged PRs in 30d

Description

  • Including a vignette explaining the ERP criterion to take into account the precision of the estimated dose-response curve during sample size calculation
  • Creating a function "simERP" that uses parametric bootstrapping to calculate ERP based on candidate models and sample sizes (+ summary and plot to see the results)
  • Modifying the plotMods function: adding optional arguments to show EDps in the plots

Contributor guide

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First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by reviewing the existing sample-size calculation entry points and the plotMods function to understand their current interfaces. Define the vignette's ERP explanation, the simERP inputs and outputs, including summary and plot results, and the optional EDps display; the work is done when these are documented and the requested functionality is covered.

Written by the indexing model from the issue text.

Assessment

Tech stack
r
Domain
data, data-visualization
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Mostly clear
Newbie friendliness
38/100

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