nf-core / nf-core/variantprioritization

Add parameter --sex

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#86 1 comment 0 reactions 1 assignee View on GitHub

@HomoPolyethylen is already working on this.

Since May 14, 2026.

  • #94 by @HomoPolyethylen — merged
enhancement
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Description

Description of feature

Hi,

Gender information is relevant to estimate the copy number state of sex chromosomes, example: Loss-of Y, XCA, etc. hence it is a relevant parameter.

When it is not provided, PCGR reports this message:

Argument --sex is 'UNKNOWN' - skipping copy number loss annotations on sex chromosomes

So, it is good to have this option added.

The tool documentation page is here:

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