ga4gh / ga4gh/vrs-python

How to handle Allele normalization for Range Locations

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#237 6 comments 0 reactions 1 assignee Assigned to @andreasprlic View on GitHub
2.0-alpha question Stale-exempt
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Python
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Description

One major theme raised in #234 is the question of "how do we handle Allele normalization when the Allele Location is specified by Ranges"? To me, these have always seemed to be a shorthand for "I did a targeted region assay and want to craft general statements about copy number in those regions and the potential broader impact they have". I know we allow people to create Alleles with Range-based Locations anyway, but... why? The PR supports those cases and raises interesting questions, e.g. what do we do with definite range intervals?

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