ga4gh / ga4gh/phenopacket-schema

Onset of first Diagnose

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Dominant language
Java
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Forks
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Description

In this [paper](https://www.nature.com/articles/s41588-025-02396-8) they use the onset of first diagnose, as a proxy for the disease onset to split their cohort into early and late onset depression.

Currently, the Diagnose data structure of the Phenopacket is missing that field. If there will be an update to the schema, it would be a delight to include it.

Contributor guide

Open the contributing guide

Research direction

Start by reading the Phenopacket schema's Diagnose definition and the linked paper to understand how onset of first diagnosis is used. Clarify whether the schema will be updated and what representation is intended; done means the requested information is specified and included in an agreed schema update.

Written by the indexing model from the issue text.

Assessment

Domain
backend-api-design
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
25/100

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