Sequences dropped by split libraries
Open
- Dominant language
- Jupyter Notebook
- Stars
- 169
- Forks
- 68
- PR merge metrics
- No merged PRs in 30d
Description
Check drop of sequences at the split library stage and if that has any correlation with env or something else.
The easiest that comes to mind to do this is to change params in split libraries to only discard sequences based on barcode and then compare the numbers per sample ...
Contributor guide
No contributing guide indexed for this repository
Research direction
Start by reproducing the split library stage and compare sequence counts per sample when filtering is limited to barcode-based discards. Determine whether sequence loss correlates with the environment or another factor, and document the observed counts and correlation.
Written by the indexing model from the issue text.
Assessment
- Tech stack
- jupyter-notebook
- Domain
- bioinformatics
- Issue type
- Bug
- Difficulty
- 4/5
- Estimated time
- 3-5 days
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 35/100