MDR-TB should be linked with treatment failure
@tdm32 is already working on this.
Since Jan 18, 2024.
- Dominant language
- Python
- Stars
- 35
- Forks
- 17
- PR merge metrics
- No merged PRs in 30d
Description
Currently TB module uses a fixed incidence to determine risk of DS or MDR-TB. MDR-TB arises independently of treatment history, assumed to be transmitted via contacts. This limitation is now apparent in the latest NTP reports showing 5x greater risk of MDR-TB with previous treatment.
One option is to have one fixed risk of active TB (rather than 2 separate risk models). The probability of a new infection being caused by either strain is a function of both the person's previous treatment history and the current prevalence of untreated infections of that strain in the population. In this way, we can capture the changing dynamics of MDR emergence/spread.
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