Only diffuse antibody CDRs while keeping FW unchanged, while specifying hotspot?

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Assessment

Difficulty
5/5
Estimated time
Over a week
Newbie friendliness
20/100
Issue type
Feature
Clarity
Needs clarification
Activity status
Stale
Tech stack
python
Domain
bioinformatics, machine-learning

Research direction

No files, tests, or entry points are named. First review how RFdiffusion currently handles antibody CDRs, framework regions, and hotspots, then clarify the intended behavior and acceptance criteria before identifying a code location.

Written by the indexing model from the issue text.

Description

Should we only diffuse antibody CDRs while keeping FW unchanged, and specify hotspot?

Dominant language
Python
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