AlexsLemonade / AlexsLemonade/refinebio
Gene fusions are of interest in the childhood cancer space.
- Dominant language
- Python
- Stars
- 135
- Forks
- 21
- PR merge metrics
- No merged PRs in 30d
Description
We may consider a processor that will convert fastq files -> gene fusion calls. @drtamermansour shared this paper that has a current benchmark.
https://www.nature.com/articles/srep21597
As this is not an immediate-term goal, I'm creating this to track thoughts in this space.
Contributor guide
No contributing guide indexed for this repository
Research direction
Start by reading the linked Nature paper and the issue discussion, although no implementation files, tests, or entry points are identified. Clarify the intended FASTQ input, gene-fusion call output, benchmark criteria, and project scope before implementation; done would require an agreed processor design and validation plan.
Written by the indexing model from the issue text.
Assessment
- Domain
- bioinformatics
- Issue type
- Feature
- Difficulty
- 5/5
- Estimated time
- Over a week
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 20/100