waldronlab / waldronlab/bugSigSimple

Create a gold standard example vignette

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#45 1 comment 0 reactions 1 assignee View on GitHub

@fiddyhamma is already working on this.

Since Jul 1, 2026.

good first issue
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Description

Using a condition with plenty of signatures (i.e. at least 30), conduct a basic analysis of those signatures using the methods established in the other vignettes. This should include:

  1. Downloading the data from BugSigDB
  2. Filtering of the data to select relevant signatures and remove similar/duplicate signatures
  3. Description of the studies
  4. Description of the taxa
  5. Basic statistical tests
  6. Monte Carlo simulation to calculate critical N
  7. Heatmaps and dendrograms

Do not reinvent the wheel! Use existing functions in bugSigSimple and draw heavily on previously written vignettes.

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