theislab / theislab/CellFlow

New `PCADecodedMetrics2` callback

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#220 1 comment 0 reactions 1 assignee View on GitHub

@LeonStadelmann is already working on this.

Since Apr 23, 2025.

enhancement
Dominant language
Python
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Description

Description of feature

PCADecodedMetrics computes metrics based on the reconstructed prediction and the reconstructed ground truth. This, in effect, gives an upper bound of CellFlow, but does not correspond to the metrics we eventually compute, as we compare the decoded generated cells with the true values, i.e. not the projected-and-then-reconstructed cells.

PCADecodedMetrics uses the adata only for the reconstruction, while the PCADecodedMetrics2 should now be used to 1) reconstruct the generated cells, and 2) to fetch the ground truth based on the condition_id_key.

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