sokrypton / sokrypton/ColabFold
complex prediction with individual MSAs per protein
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Description
Hi there
I am trying to query a set of proteins for complexes against a larger proteome database
I have precomputed MSAs (a3m) files for each of the individual proteins
How can I provide them to the colabfold_batch step when providing the complex as the fasta input (proteins seperated by ':')
Thank you!
Contributor guide
First steps
- Read the whole issue, then the project's contributing guide.
- Comment on the issue to say you are picking it up — it saves two people doing the same work.
- Fork the repository and make your change on a branch.
- Open a pull request that references the issue number.
Research direction
Start with the colabfold_batch entry point and its handling of colon-separated complex FASTA inputs; inspect how the supplied a3m files are accepted. Done means documenting or confirming whether separate precomputed MSAs can be provided for each protein in a complex.
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Assessment
- Domain
- bioinformatics
- Issue type
- Documentation
- Difficulty
- 3/5
- Estimated time
- 1-2 days
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 25/100