sokrypton / sokrypton/ColabFold

predicting only one complex using fasta input that includes multiple entries

Open
#750 2 comments 0 reactions 0 assignees View on GitHub

Nobody has claimed this yet.

Dominant language
Jupyter Notebook
Stars
2.9k
Forks
747
PR merge metrics
No merged PRs in 30d

Description

Hi,

I am using AlphaFold2_batch (https://colab.research.google.com/github/sokrypton/ColabFold/blob/main/batch/AlphaFold2_batch.ipynb) and placed a fasta file containing multiple pairs of protein:peptide sequences like this

FBP0001
PIAQIHILEGRSDEQKETLIREVSEAISRSLDAPLTSVRVIITEMAKGHFGIGGELASK:FLLKQIEF
FBP0002
PIAQIHILEGRSDEQKETLIREVSEAISRSLDAPLTSVRVIITEMAKGHFGIGGELASK:IEFLKGQLPEAPVI

I did get the results but it only predicted the first entry within the fasta.

Did I get anything wrong in my input fasta?
I did not change any codes.

Anyone coming across the same issue before?

Thanks!

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start with the AlphaFold2_batch notebook linked in the issue and reproduce the run using the two-entry FASTA input shown. Trace how multiple FASTA entries are read and determine whether both complexes are processed; done means the notebook handles the documented multi-entry input or clearly reports the supported format.

Written by the indexing model from the issue text.

Assessment

Tech stack
jupyter-notebook
Domain
bioinformatics
Issue type
Bug
Difficulty
3/5
Estimated time
1-2 days
Activity status
Stale
Clarity
Mostly clear
Newbie friendliness
35/100

Get new issues in your inbox

A short digest of beginner-friendly GitHub issues.