sokrypton / sokrypton/ColabFold

Does sequence order matter when predicting complex

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Description

Hello,
I have a simple question.
If I want to predict the structure of a heterodimer,
is it necessary to switch the order of the two sequences, or will any combination work?
Thanks in advance.

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Research direction

No files, tests, or entry points are mentioned. First clarify whether this is asking for an answer or a documentation change, then verify the expected behavior for heterodimer sequence ordering and document the conclusion in the appropriate ColabFold usage guidance.

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Assessment

Domain
bioinformatics
Issue type
Documentation
Difficulty
1/5
Estimated time
Under an hour
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
20/100

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