sokrypton / sokrypton/ColabFold

Online colabfold can use PDB-s as templates, local cannot

Open
#445 1 comment 0 reactions 0 assignees View on GitHub

Nobody has claimed this yet.

Dominant language
Jupyter Notebook
Stars
2.9k
Forks
747
PR merge metrics
No merged PRs in 30d

Description

Hi,

I am trying to repeat a run that I did online, with the local version of ColabFold. Online, I can use PDB-s as inputs, but locally it contains that it cannot find cif files.
I used the following flags:
--msa-mode single_sequence --templates --custom-template-path $outdir/template
Am I doing sth wrong or this is not a feature of the local version?

Thank you,
Julia

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by reproducing the run with --templates, --custom-template-path, and --msa-mode single_sequence using the reported PDB inputs. Compare the local and online template-input behavior, then determine whether local ColabFold should accept PDB files; done means the local workflow supports the same input or the limitation is clearly established.

Written by the indexing model from the issue text.

Assessment

Domain
bioinformatics
Issue type
Feature
Difficulty
4/5
Estimated time
3-5 days
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
25/100

Get new issues in your inbox

A short digest of beginner-friendly GitHub issues.