Using encryption (journeyapps/sqlcipher) in sqllite, there is no problem with normal use, but an error will be reported when using transactions

Environment version

nodejs：V14.15.0
sqlite3@^5.1.4
journeyapps/sqlcipher@^5.3.1
sequelize@^6.29.0

This is the database related configuration

`
const path = require("path");
const { Sequelize } = require('sequelize');
const file = path.join(__dirname, '../ecg.db');
const LOG = require("./log4js").logger("SequelizeConnectDb");

const sequelize = new Sequelize({
pool: {
max: 5,
min: 0,
acquire: 30000,
idle: 10000
},
dialect: 'sqlite',
storage: file,
dialectModulePath: '@journeyapps/sqlcipher',
logging: false,
logging: msg => LOG.info(msg)
});

sequelize.query('PRAGMA cipher_compatibility = 3');
sequelize.query("PRAGMA key = 'xxx'");

//使用 .authenticate() 函数测试连接是否正常
sequelize.authenticate().then(() => {
LOG.info('Connection has been established successfully.')
}).catch(err => {
LOG.error('Unable to connect to the database:', err)
})

module.exports = sequelize;
`

Using transactions will result in an error

`
let transaction = null;
let ecgEntity = null;
let hasError = false;
let err = null;
try {
transaction = await sequelize.transaction();
ecgEntity = await ecg.create(this.buildEcgData(ecgInfo, user), { transaction });

        await ecg.update({ filePath: AppConfig.getHolterRootPath(ecgEntity.id) }, { where: { id: ecgEntity.id }, transaction });
        await bpDetail.bulkCreate(this.buildBpData(ecgEntity, bpList), { transaction });
    } catch (e) {
        await transaction.rollback();
    }

`

Error Message

'SQLITE_NOTADB: file is not a database'
'Error\n at Database. (F:\Code\ECGBP\trunk\holter-bp\node_modules\sequelize\lib\dialects\sqlite\query.js:185:27)\n at Database.callbackTrampoline (internal/async_hooks.js:129:14)\n at F:\Code\ECGBP\trunk\holter-bp\node_modules\sequelize\lib\dialects\sqlite\query.js:183:50\n at new Promise ()\n at Query.run (F:\Code\ECGBP\trunk\holter-bp\node_modules\sequelize\lib\dialects\sqlite\query.js:183:12)\n at F:\Code\ECGBP\trunk\holter-bp\node_modules\sequelize\lib\seque…CGBP\trunk\holter-bp\node_modules\sequelize\lib\dialects\abstract\query-interface.js:308:21)\n at async model.save (F:\Code\ECGBP\trunk\holter-bp\node_modules\sequelize\lib\model.js:2490:35)\n at async Function.create (F:\Code\ECGBP\trunk\holter-bp\node_modules\sequelize\lib\model.js:1362:12)\n at async DBService.beginImport (F:\Code\ECGBP\trunk\holter-bp\areas\system\service\ecgFileService.js:92:25)\n at async F:\Code\ECGBP\trunk\holter-bp\areas\system\service\ecgFileService.js:542:35'

Reproduce the transaction in areas/system/service/ecgFileService.js with the listed Node.js, sqlite3, SQLCipher, and Sequelize versions, then inspect the stack around node_modules/sequelize/lib/dialects/sqlite/query.js:183-185. Confirm whether the encrypted database opens normally but fails during transaction queries, and establish the minimal reproducible scope and expected behavior.