scverse / scverse/squidpy

Tutorial request: Stereo-seq (BGI STOmics) analysis — bin vs cellbin

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Dominant language
Python
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598
Forks
121
Avg merge
3d 11h
Merged PRs (30d)
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Description

Description of feature

First, thanks for squidpy — the per-platform tutorials (Visium, Xenium, MERFISH,
seqFISH, Slide-seqV2, Vizgen, IMC, MIBI-TOF, CosMx, 4i) are extremely useful.

One major platform is missing: Stereo-seq (BGI / STOmics). It's one of the
most widely used spatial transcriptomics technologies (large-FOV whole-organ /
whole-embryo atlases), and many of us run squidpy on it, but there is no official
guidance — so people keep guessing at the correct setup. Would the maintainers
(or community) consider adding a Stereo-seq tutorial? I'm happy to help and can
provide real data for testing.

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Review the existing per-platform tutorials in Squidpy and determine what Stereo-seq data and setup guidance are needed for bin versus cellbin analysis. A suitable outcome is an official Stereo-seq tutorial with reproducible examples and clear recommendations for both workflows; the issue offers real data for testing but names no files or tests.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
documentation
Issue type
Documentation
Difficulty
4/5
Estimated time
3-5 days
Activity status
Quiet
Clarity
Needs clarification
Newbie friendliness
45/100

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