scverse / scverse/spatialdata

Improve compatibility of cell segmentation output formats with downstream analysis tools

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Dominant language
Python
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Forks
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4d 3h
Merged PRs (30d)
7

Description

The cell segmentation (HD and stereoseq)results from spatialdata are currently difficult to integrate with downstream analysis software.
The main issue is with the saved format, especially the image/labels format, which doesn't connect well with many commonly used downstream tools (like Seurat, scanpy, and other spatial analysis packages).
Could the team consider:

Adding export functions to convert segmentation results to more widely-compatible formats
Providing clearer documentation on how to bridge spatialdata outputs with popular downstream tools

This would greatly improve the usability of spatialdata in standard spatial transcriptomics analysis workflows.

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Research direction

Start by reviewing how spatialdata currently saves HD and stereoseq cell-segmentation image and labels results. Identify the compatibility requirements of Seurat, scanpy, and other spatial analysis tools, then determine whether export functions, bridging documentation, or both are needed. Done means segmentation results can be used more easily in standard spatial transcriptomics workflows.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
data
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
30/100

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