scverse / scverse/spatialdata-io

filtered_counts_file parameter for cell-segmented matrices

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visium-hd
Dominant language
Python
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Description

Hello!

Is there a chance that the filtered_counts_file parameter of the visium_hd reader can apply to cell-segmented matrices as well?

For example here, when I set the filtered_counts_file to False:

sdata = visium_hd(
    path=crc_spaceranger_outs,
    dataset_id='CRC',
    filtered_counts_file=False,
    load_segmentations_only=True
)

it still loads the number of observations in filtered_feature_cell_matrix.h5 instead of raw_feature_cell_matrix.h5.

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Research direction

Start at the visium_hd reader and trace how filtered_counts_file is handled when load_segmentations_only=True. Compare the observation count loaded from filtered_feature_cell_matrix.h5 with the expected raw_feature_cell_matrix.h5 behavior, then add or update coverage for this parameter combination.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
data
Issue type
Bug
Difficulty
3/5
Estimated time
1-2 days
Activity status
Quiet
Clarity
Mostly clear
Newbie friendliness
65/100

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