scverse / scverse/scirpy

New tutorial: query tetramer-staining datasets

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Description

Description of feature

Show that we can not only query referene databases, but also other datasets, e.g. from Tetramer or Dextramer staining.

10x provides some dataset

You could use the BEAMT sample data from 10x for human or mouse? It has clear epitope information and the GEX/Antigen quantification - here is an example of the human EBV/HLA-A*11 public data they have: https://www.10xgenomics.com/datasets/10k-human-a1101-pbmcs-with-ebv-spike-in-beam-t-2-standard#

CC @ncborcherding @RaphaelDeGottardi

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

No file, test, or entry point is named. Start by reviewing the repository's existing tutorial structure and the linked 10x BEAM-T dataset, then determine how its tetramer or dextramer, epitope, GEX, and antigen-quantification data should be queried. Done means a tutorial demonstrates querying a non-reference dataset with the human or mouse sample.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
data, documentation
Issue type
Documentation
Difficulty
3/5
Estimated time
1-2 days
Activity status
Quiet
Clarity
Mostly clear
Newbie friendliness
54/100

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