Clonotype dotplot
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- Dominant language
- Python
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Description
In GitLab by @grst on Mar 31, 2020, 16:56
Scanpy has the dotplot with dendrogram for genes, which I find pretty cool. I would imagine it a good chance to get some overview on the whole dataset to show samples, top clonotype, the size of those clonotypes and either the expansion or the publicness/privateness of that clonotype (later, when we have a nice measure for that)

So this could either be:
- the n-top clonotypes of each sample (which would also give us information about how private/public a clonotype is (if it is expanded in multiple samples). However, in most cases they are at least not shared between patients and the plot would look quite sparse.
- The size of the top n clonotypes for each sample (on the x axis would be no specific clonotypes, just the rank). This would give us similar information as the clonal expansion plot
Contributor guide
First steps
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Research direction
Start by reviewing the Scanpy dotplot with dendrogram referenced in the issue and compare the two proposed views: top clonotypes per sample or ranked clonotype sizes. The issue does not name files, tests, an entry point, or a settled definition of done; clarify the visualization design and expected clonotype measures before implementation.
Written by the indexing model from the issue text.
Assessment
- Tech stack
- python
- Domain
- bioinformatics, data-visualization
- Issue type
- Feature
- Difficulty
- 5/5
- Estimated time
- Over a week
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 25/100