Public and private epitopes
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- Python
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Description
In GitLab by @szabogtamas on Feb 19, 2020, 14:04
In publications, people commonly refer to CDR3s shared by most individuals in a group (patients) as a public chain. We should also consider if we want to offer a function to detect public CDRs and if this should just return a list or try to visualize something.
Another consideration is whether or not we should creat a metric that tells us how public is a CDR3 (maybe the diversity of the grouping variable among the cells having tat specific CDR3).
Contributor guide
First steps
- Read the whole issue, then the project's contributing guide.
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Research direction
The issue names no files, tests, or entry points. Begin by clarifying whether the goal is public-CDR3 detection, visualization, a publicness metric, or all three, and define the grouping variable and expected outputs from the cited publication context. Done should include an agreed scope and measurable behavior before implementation starts.
Written by the indexing model from the issue text.
Assessment
- Tech stack
- python
- Domain
- bioinformatics
- Issue type
- Feature
- Difficulty
- 5/5
- Estimated time
- Over a week
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 20/100