scverse / scverse/scanpy

FIt-SNE integration?

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Description

  • Additional function parameters / changed functionality / changed defaults?
  • New analysis tool: A simple analysis tool you have been using and are missing in sc.tools?
  • New plotting function: A kind of plot you would like to seein sc.pl?
  • External tools: Do you know an existing package that should go into sc.external.*?
  • Other?

...

Hi!

We're considering implementing some of the t-SNE recommendations in https://www.nature.com/articles/s41467-019-13056-x for our single-cell analysis. They use a different t-SNE implementation (https://github.com/KlugerLab/FIt-SNE), and before I ran off doing my own wrapping and plumbing to integrate with Scanpy I thought I'd check: have you considered integrating this yourselves?

Thanks!

Jon

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by reviewing the sc.tools entry points and the cited FIt-SNE package, then compare the requested integration with the referenced t-SNE recommendations. Done requires an agreed scope for integrating FIt-SNE into Scanpy; the issue names no files or tests and leaves the implementation details open.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
bioinformatics, machine-learning
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
25/100

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