rank_genes_groups one- or two-sided test
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- Python
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Description
Hi!
Is it possible to do two-sided (or two-tailed) test in rank_genes_groups?
It seems like the tests you can choose from for now (t-test, wilcoxon etc.) are one-sided in that comparing group A to group B produces a list of DE genes that is not the same as in comparison of B to A.
Thank you.
Sincerely,
Anna Arutyunyan
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Research direction
Start at the rank_genes_groups entry point and determine how its supported tests handle group direction and tail selection. Define the expected two-sided behavior, including whether reversing the compared groups should produce the same differential-gene results, then add coverage for that behavior.
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Assessment
- Tech stack
- python
- Domain
- bioinformatics
- Issue type
- Feature
- Difficulty
- 5/5
- Estimated time
- Over a week
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 30/100