Add Poisson Gene Selection to HVG
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- Dominant language
- Python
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- Merged PRs (30d)
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Description
What kind of feature would you like to request?
Additional function parameters / changed functionality / changed defaults?
Please describe your wishes
Add Analytical Poisson Geneselection to scanpy HVG. SCVI has MonteCarlo approach while Rapids-singlcell offers and analytical solution
Contributor guide
First steps
- Read the whole issue, then the project's contributing guide.
- Comment on the issue to say you are picking it up — it saves two people doing the same work.
- Fork the repository and make your change on a branch.
- Open a pull request that references the issue number.
Research direction
Start by reviewing Scanpy's existing HVG functionality and the analytical approach offered by Rapids-singlecell, while comparing it with SCVI's Monte Carlo approach. Define the requested Poisson gene-selection parameters, expected behavior, and validation criteria before identifying tests. Done means Scanpy supports and validates analytical Poisson HVG selection.
Written by the indexing model from the issue text.
Assessment
- Tech stack
- python
- Domain
- bioinformatics
- Issue type
- Feature
- Difficulty
- 5/5
- Estimated time
- Over a week
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 25/100