scverse / scverse/scanpy

Apple Silicon: Accelerate or openBLAS for Numpy

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Question
Dominant language
Python
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Merged PRs (30d)
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Description

What kind of feature would you like to request?

Additional function parameters / changed functionality / changed defaults?

Please describe your wishes

After naively updated my apple OS to tahoe, my UMAPs and leiden clustering result in slightly different outputs. I learned from chatGPT that this is probably due to an update of the accelerate BLAS that my Numpy accesses. I could use OpenBLAS which would be independent from Apple updates, but performs even more distinct.

What is the general recommendation for scanpy usage?

Contributor guide

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First steps

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Research direction

The issue names no files, tests, or entry points. Start by determining whether Scanpy or NumPy controls the Apple Silicon BLAS choice and what recommendation is expected for UMAP and Leiden results; done would require a clearly scoped recommendation or change.

Written by the indexing model from the issue text.

Assessment

Tech stack
numpy, python
Domain
bioinformatics, performance
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
25/100

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