scverse / scverse/scanpy

Add scran nomalisation into scanpy

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#3,255 2 comments 0 reactions 0 assignees View on GitHub

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Area – Preprocessing 🧼
Dominant language
Python
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Merged PRs (30d)
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Description

What kind of feature would you like to request?

New analysis tool: A simple analysis tool you have been using and are missing in sc.tools?

Please describe your wishes

As previously attempted (#823), it would be amazing to have scran normalisation implemented in scanpy.
It's one of the best practices and for many simple analysis workflows, it might even be the only step currently requiring to switch to R.

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by reviewing the previous attempt in #823 and the existing sc.tools analysis-tool conventions. Consult the linked best-practices description to understand the requested scran normalization workflow. Done means scanpy provides scran normalization as a usable analysis tool without requiring users to switch to R.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
data
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
30/100

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