Is it possible to test for bimodality in scanpy?
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Description
Is there a way to test if particular genes of a single-cell-RNA-seq-dataset show bimodal distributions, in order to infer heterogeneity?
e.g. like in: https://www.nature.com/articles/nature13437
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First steps
- Read the whole issue, then the project's contributing guide.
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Research direction
Start by reviewing the bimodality-testing question and the linked Nature article. The issue names no Scanpy file, entry point, or test, and does not define whether the outcome should be an API, analysis workflow, or documentation; a completed change would need a clearly specified scope and validation criteria.
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Assessment
- Tech stack
- python
- Domain
- bioinformatics
- Issue type
- Feature
- Difficulty
- 5/5
- Estimated time
- Over a week
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 20/100