scverse / scverse/SnapATAC2

Adding broad peak calling option in MACS3 function?

Open
#210 1 comment 0 reactions 0 assignees View on GitHub

Nobody has claimed this yet.

enhancement :sparkles:
Dominant language
Python
Stars
323
Forks
43
PR merge metrics
No merged PRs in 30d

Description

Hi Kai,

First of all, thank you for developing snapATAC2!

I was wondering if we could have the option to call broad peak when using macs3. I see that it's currently not supported.

Thank you!
Zhenkun

Contributor guide

No contributing guide indexed for this repository

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by locating the SnapATAC2 entry point that invokes MACS3 for peak calling and inspect how its current options are exposed. Add a broad-peak option only if the existing integration supports it, and verify that users can select it while retaining the current default behavior.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
bioinformatics
Issue type
Feature
Difficulty
3/5
Estimated time
1-2 days
Activity status
Stale
Clarity
Mostly clear
Newbie friendliness
35/100

Get new issues in your inbox

A short digest of beginner-friendly GitHub issues.