scverse / scverse/PyDESeq2

fitType = local for vst function

Open
#154 3 comments 0 reactions 0 assignees View on GitHub

Nobody has claimed this yet.

enhancement
Dominant language
Python
Stars
761
Forks
90
Avg merge
25m
Merged PRs (30d)
10

Description

Is your feature request related to a problem? Please describe.
vst doent have 'local' as a fitType option

Describe the solution you'd like
If vst could also have local as an option, that would be great

Describe alternatives you've considered
Alternatively, I just import my code into R and do it from there

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by locating the vst entry point and the handling of fitType options in PyDESeq2. Compare the existing options with the requested local behavior and identify relevant tests or examples before making a change. Done means vst accepts fitType='local' and its behavior is covered by tests.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
bioinformatics
Issue type
Feature
Difficulty
4/5
Estimated time
3-5 days
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
35/100

Get new issues in your inbox

A short digest of beginner-friendly GitHub issues.