HOB,ICB annotation for non-ref HET and multiallelic sites

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Assessment

Difficulty
4/5
Estimated time
3-5 days
Newbie friendliness
25/100
Issue type
Bug
Clarity
Needs clarification
Activity status
Stale
Tech stack
c
Domain
bioinformatics

Research direction

Start by locating the HOB and ICB annotation calculations in the bcftools source and identify how non-reference heterozygous and multiallelic sites are currently handled. Reproduce the issue with representative variant records, then verify that both annotations account for those cases.

Written by the indexing model from the issue text.

Description

enhancement

These calculations do not take into account non-ref HETs and multiallelic sites.

Dominant language
C
Stars
891
Forks
277
Avg merge
2d 23h
Merged PRs (30d)
2

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