rrwick / rrwick/Badread

High Memory consumption causes computer to freeze

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Dominant language
Python
Stars
302
Forks
25
PR merge metrics
No merged PRs in 30d

Description

I'm trying to generate multiple transcriptomic datasets in parallel with different parameters (error model, coverage/depth, and sequence identity), however, Badread consumes a lot of memory while doing this and occasionally will cause my machine to freeze while running the simulation.

Is there a way to control the memory usage, or better optimize the process of simulating multiple datasets in parallel?

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Research direction

The issue names parallel transcriptomic dataset generation with varying error model, coverage/depth, and sequence identity, but it does not identify a file, test, or entry point. Start by reproducing the parallel simulation and measuring memory usage across those parameters. Done would require an agreed way to control or reduce memory use without freezing the machine.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
bioinformatics, performance
Issue type
Bug
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
25/100

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