nf-core / nf-core/phaseimpute

Add post-imputation filter step

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enhancement
Dominant language
Nextflow
Stars
35
Forks
23
Avg merge
16d 3h
Merged PRs (30d)
1

Description

Description of feature

Imputed variants should be filter based on the GP field and a given threshold.

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by tracing the pipeline's post-imputation workflow and identify where imputed variants are emitted. Determine how the GP field and a user-provided threshold should be exposed and applied, then verify that variants below the threshold are filtered from the output.

Written by the indexing model from the issue text.

Assessment

Domain
bioinformatics
Issue type
Feature
Difficulty
3/5
Estimated time
1-2 days
Activity status
Quiet
Clarity
Mostly clear
Newbie friendliness
48/100

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