nf-core / nf-core/modules

New module: motifmatchr/matchmotifs

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Description

Module

Add motifmatchr/matchmotifs.

Purpose

The component scans BED regions against a JASPAR-format position frequency matrix collection and a reference FASTA. It emits a sparse Matrix Market motif-match matrix plus explicit row and column mapping tables.

This provides a reusable, lightweight annotation step for chromVAR and other motif-based workflows while keeping motif scanning separate from downstream statistical analysis.

Software

  • bioconductor-motifmatchr 1.32.0
  • Public Biocontainers image: quay.io/biocontainers/bioconductor-motifmatchr:1.32.0--r45ha27e39d_0

Validation

  • nf-core module lint: 53 passed, 0 failed
  • Docker test and stub test passed with nf-test

I will submit the implementation from my fork.

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start with the motifmatchr/matchmotifs module entry and the biocontainers motifmatchr:1.32.0 image. Review the stated nf-core module lint, Docker test, and stub test validation, then confirm the module scans the BED, JASPAR-format matrix, and FASTA inputs and emits the sparse matrix plus row and column mappings.

Written by the indexing model from the issue text.

Assessment

Tech stack
r
Domain
bioinformatics
Issue type
Feature
Difficulty
3/5
Estimated time
1-2 days
Activity status
Active
Clarity
Clearly specified
Newbie friendliness
35/100

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