new module: cnvkit/referencepooled
Nobody has claimed this yet.
- Dominant language
- Nextflow
- Stars
- 429
- Forks
- 1.1k
- Avg merge
- 1d 6h
- Merged PRs (30d)
- 153
Description
Is there an existing module for this?
- I have searched for the existing module
Is there an open PR for this?
- I have searched for existing PRs
Is there an open issue for this?
- I have searched for existing issues
Further Information
As mentioned in #12656, currently the cnvkit/reference module only seems to support generating a flat reference as you cannot provide coverage files to generate a pooled normal reference. Providing per-sample coverage files is mutually exclusive with the --targets/--antitargets flags (CNVkit's reference subcommand has two distinct modes and refuses to combine them), so a new module for generating a pooled reference is required
Are you going to work on this?
- If I'm planning to work on this module, I added myself to the
Assigneesto facilitate tracking who is working on the module
Software requirements (conda)
---
# yaml-language-server: $schema=https://raw.githubusercontent.com/nf-core/modules/master/modules/environment-schema.json
channels:
- conda-forge
- bioconda
dependencies:
- bioconda::cnvkit=0.9.14
Contributor guide
First steps
- Read the whole issue, then the project's contributing guide.
- Comment on the issue to say you are picking it up — it saves two people doing the same work.
- Fork the repository and make your change on a branch.
- Open a pull request that references the issue number.
Research direction
Read the existing cnvkit/reference module and the context in issue #12656 first, then review CNVkit 0.9.14's pooled-reference mode and the repository's module conventions. Done means adding cnvkit/referencepooled so per-sample coverage files can generate a pooled normal reference without combining them with --targets or --antitargets.
Written by the indexing model from the issue text.
Assessment
- Domain
- bioinformatics
- Issue type
- Feature
- Difficulty
- 4/5
- Estimated time
- 3-5 days
- Activity status
- Quiet
- Clarity
- Mostly clear
- Newbie friendliness
- 55/100