nf-core / nf-core/modules

new module: poppunk/createdb

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#11,084 0 comments 0 reactions 1 assignee View on GitHub

@cwoodside1278 is already working on this.

Since Mar 29, 2026.

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Description

Is there an existing module for this?
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Further Information

PopPUNK (Population Partitioning Using Nucleotide Kmers) is a tool for rapid bacterial genome clustering that uses variable-length k-mer distances to define and assign strains at population scale. The --create-db subcommand is the first step in the PopPUNK workflow, taking a set of input assemblies and generating a database of k-mer sketches along with a matrix of pairwise core and accessory distances. This database is then used by downstream PopPUNK commands (such as --fit-model or poppunk_assign) to cluster genomes into strains or assign new queries to existing clusters.

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