nf-core / nf-core/methylseq

Add SNP calling

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#65 6 comments 0 reactions 0 assignees View on GitHub

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enhancement
Dominant language
Nextflow
Stars
198
Forks
181
Avg merge
6d 17h
Merged PRs (30d)
1

Description

It would be nice to be able to have the option of calling variants from bisulfite data.

It shouldn't be too tricky to add Bis-SNP or something similar as a new opt-in process. There may be other / better tools also?

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by reviewing the Bis-SNP project linked in the issue and compare it with other possible tools for calling variants from bisulfite data. Determine the scope of an opt-in process and define completion as a supported variant-calling option for this data type.

Written by the indexing model from the issue text.

Assessment

Domain
bioinformatics
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
30/100

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