nf-core / nf-core/genomeassembler

issues with genomescope2 module

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bug
Dominant language
Nextflow
Stars
34
Forks
22
Avg merge
1d 13h
Merged PRs (30d)
13

Description

Description of the bug

When attempting to switch to nf-core/genomescope to as part of #171, genomescope2 failed to converge for the full_test dataset.
The currently local genomescope module (genomescope.R in bin/) works fine and converges. The reasons for this are unclear, but may be worth figuring out.

Command used and terminal output

Relevant files

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System information

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Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Compare the nf-core/genomescope2 module with the local bin/genomescope.R implementation, using the full_test dataset and the context from issue #171. Reproduce the failure and investigate why genomescope2 does not converge; done means the full_test run converges successfully or the incompatibility is documented with evidence.

Written by the indexing model from the issue text.

Assessment

Tech stack
r
Domain
bioinformatics
Issue type
Bug
Difficulty
4/5
Estimated time
3-5 days
Activity status
Quiet
Clarity
Needs clarification
Newbie friendliness
42/100

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