nf-core / nf-core/fetchngs

add --save_merged_fastq for merging technical repeats to fetchngs

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#95 5 comments 1 reaction 0 assignees View on GitHub

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enhancement
Dominant language
Nextflow
Stars
202
Forks
93
Avg merge
1d 18m
Merged PRs (30d)
15

Description

Description of feature

Hi nfcore/fetchngs team,

It would be awesome to add --save_merged_fastq for merging technical repeats to fetchngs. Would be very useful for downstream programs that cant deal with technical repeats.

Often easy to identify technical repeats from GEO because although technical repeats each have unique run_accession they share the same experiment_alias.

Many thanks,
Oliver

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First steps

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Research direction

Start by locating fetchngs's command-line option handling and workflow entry point, then trace how technical repeats are represented by shared experiment_alias values. Done means --save_merged_fastq merges those repeats and produces saved merged FASTQ files for downstream use.

Written by the indexing model from the issue text.

Assessment

Domain
bioinformatics, data-engineering
Issue type
Feature
Difficulty
4/5
Estimated time
3-5 days
Activity status
Stale
Clarity
Mostly clear
Newbie friendliness
35/100

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