nf-core / nf-core/eager

Add --platypus option to PMDtools

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#349 8 comments 0 reactions 2 assignees View on GitHub

@TCLamnidis is already working on this.

Since Mar 22, 2021.

  • #353 by @jfy133 — closed without merging
  • #708 by @TCLamnidis — merged
help wanted needs upstream fix partially-fixed pending
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Description

Is your feature request related to a problem? Please describe.

@pontussk suggests including the possibility for users to run PMDtools with the following flag --platypus. This is apparently used for mammals nDNA, as CpG cytosines are not affected by UDG treatment (and you can use it to see damage patterns still in UDG treatment, when using alongside --deamination!).

he also recommends including --first and --CpG

I will add those flags and maybe ask him to contribute some documentation (or 'recommendations' when to use those flags).

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