nf-core / nf-core/crisprseq

Pass file to cutadapt

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#107 2 comments 0 reactions 0 assignees View on GitHub

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enhancement
Dominant language
Nextflow
Stars
63
Forks
39
PR merge metrics
No merged PRs in 30d

Description

Description of feature

Thanks for developing this useful pipeline.

I was wondering if it's possible to run the screening pipeline with cutadapt specifying fasta file of multiple adaptor sequences e.g. like here. I have tried trying to pass --cutadapt file:adapters.fasta to the nextflow pipeline, however, I receive an error stating that the 'adapters.fasta' file cannot be found, even though it is there locally.

I am running nextflow version 23.10.1, crisprseq v2.1.1, with singularity as a profile.

Thanks for your help.

Contributor guide

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First steps

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  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by tracing the screening pipeline's --cutadapt parameter and how adapters.fasta is passed to the cutadapt process; the issue names no repository files or tests. Check the pipeline's file-input handling with the provided multi-sequence adapters.fasta under the Singularity profile. Done means a local adapter FASTA can be supplied and used successfully.

Written by the indexing model from the issue text.

Assessment

Domain
bioinformatics
Issue type
Feature
Difficulty
4/5
Estimated time
3-5 days
Activity status
Stale
Clarity
Mostly clear
Newbie friendliness
35/100

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