nf-core / nf-core/createpanelrefs
Support creating a PoN with PureCN
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@lbeltrame is already working on this.
Since Oct 29, 2024.
enhancement
- Dominant language
- Nextflow
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- 11
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- 16
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- No merged PRs in 30d
Description
Description of feature
This came up during the Barcelona Hackathon. PureCN can build a panel of normals "database" from coverage data and an optional VCF (https://www.bioconductor.org/packages/devel/bioc/vignettes/PureCN/inst/doc/Quick.html#42_NormalDB).
Since PureCN doesn't support CRAM files at the moment (https://github.com/lima1/PureCN/issues/244) the plan is to use GATK denoised coverage data.
Adding this so I won't forget.
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