Pocock-Simon minimization
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- Dominant language
- R
- Stars
- 10
- Forks
- 1
- PR merge metrics
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Description
On #60 I realized that there are previous research on this area and this is solved with exact solutions using "Pocock-Simon minimization". [This minimization](https://en.wikipedia.org/wiki/Minimisation_(clinical_trials)) offers exact solutions in some cases (two arms).
There are [some packages on CRAN](https://search.r-project.org/?P=Pocock-Simon+minimization&DEFAULTOP=and&DB=all&FMT=query&xDB=all&xFILTERS=.%7E%7E) that provide it. Specially RobinCar2.
Exploring and see what experDesign can offer compared to that package might be helpful for users and this package.
Contributor guide
First steps
- Read the whole issue, then the project's contributing guide.
- Comment on the issue to say you are picking it up — it saves two people doing the same work.
- Fork the repository and make your change on a branch.
- Open a pull request that references the issue number.
Research direction
Start with issue #60 and review the linked CRAN search results, especially RobinCar2, to understand Pocock-Simon minimization and its exact two-arm solutions. Compare those capabilities with experDesign and define what this package should offer; done means a documented, agreed scope and an implementation plan.
Written by the indexing model from the issue text.
Assessment
- Tech stack
- r
- Domain
- data
- Issue type
- Feature
- Difficulty
- 5/5
- Estimated time
- Over a week
- Activity status
- Quiet
- Clarity
- Needs clarification
- Newbie friendliness
- 25/100